However, the anti-aging effects of SYR via antioxidant and autophagy regulation have not been elucidated.

Syringaresinol (SYR), isolated from Panax ginseng berry, has various physiological activities, including anti-inflammatory action. Collagens in the ECM are cleaved by matrix metalloproteinases (MMPs).

In aged skin, reactive oxygen species (ROS) induces degradation of the extracellular matrix (ECM), leading to visible aging signs.